Grossly, the lesion of IPEH appears as a smooth, blue-gray mass that is round or oval. The wall of the vein is in fact the circumscribed wall of the lesion. Microscopically, the tumor consists of papillary fronds lined by single or multiple layers of proliferated endothelial cells with no atypia. Other features such as fibrin deposition, degree of collagenization, and the inflammatory cell component depend on the age of the throm-bus.77,81 The histopathologic differential diagnosis includes angiosarcoma and angiolymphoid hyperplasia with eosinophilia (Kimura disease).81
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