Management and Prognosis

Orbital leiomyoma is a benign tumor; the best treatment is complete surgical excision.101 The prognosis is still excellent for tumors that have been incompletely excised and later, having recurred locally, have been completely excised.

Transformation of an incompletely excised and irradiated orbital leiomyoma into leiomyosarcoma has been reported, but it is quite possible that the high doses of external beam radiotherapy (115 Gy) might have contributed to the development of sarcomatous transformation in that case.101

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