The incidence of disease processes of the orbit and ocular adnexa, both infective and neoplastic, has changed over time and varies enormously in geographic distribution. These trends have been largely due to changes in the incidence of infections with some bacteria and viruses. In addition, our understanding of the role of infectious agents in the development of neoplasms has increased, and it is likely that their role is greater than had been recognized in a large number of orbital and ocular adnexal neoplasms.
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