As the name implies, this lesion is a neoplasm but evidence suggests that peripheral ossifying fibroma originates as a reactive lesion, an inflammatory fibrous hyperplasia. These lesions are more common in the young and in females. They appear as a nodular mass and are not known to occur at sites other than the gingiva. The color is normal-to-red, and the size seldom exceeds 2.0 cm. Large lesions may cause the separation of teeth. The typical histologic finding is a proliferation of benign, cellular, fibrous connective tissue from which arise trabeculae of bone or droplets of acellular calcified matrix, putative cementum. The base of the lesion may harbor a florid infiltrate of plasma cells. Treatment is surgical excision and the recurrence rate is approximately 15%. Multiple recurrences are not uncommon.
Was this article helpful?