In eyes with vitreous hemorrhage, red blood cells occasionally undergo a degenerative process and their cell wall is altered so that these khaki-colored cells become rigid and oval. If the anterior hyaloid face is disrupted or absent, these cells can enter the AC but are unable to exit through normal outflow channels, obstructing the trabecular meshwork. The condition can occur after closed or open globe trauma .
Regarding therapy, vitrectomy is necessary to remove the reservoir of the ghost cells and AC lavage to cleanse the outflow channels .
Irrigation of the AC for eyes with glaucoma secondary to ghost cells will not permanently reduce the IOP if the resupply of such cells from the vitreous cavity has not been addressed.
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