Factors That Contribute To Obstructive Sleep Apnea

The reasons for gender differences in OSA may be traced to differences in the individual factors that contribute to OSA (Table 1). The pathophysiology of upper airway collapse during sleep is multifactorial, and differences in these factors between genders will elucidate the varied presentations.

TABLE 1 Factors Responsible for Obstructive Sleep Apnea with Potential Gender Differences

Anatomic

Physiologic

Other

Upper airway anatomy Upper airway compliance Body habitus

Local neuromuscular reflexes Alcohol, tobacco, or drug use Central ventilatory control Hormonal effects Arousal response

Sleep Apnea

Sleep Apnea

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