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Coronary Artery Disease

Resting Ejection Fraction

Myocardial Infarction

In the pre-thrombolytic era, the EF was the most important indicator of survival following infarction. Although the EF remains an important prognostic indicator, patients who receive thrombolytic treatment have a substantially lower mortality for any level of ejection fraction. Assessment of ventricular function within the first few days after myocardial infarction may be influenced by compensatory hyperkinesis of non-infarcted segments (increasing the EF) or by hypokinesis of "stunned" myocardium (lowering the EF). A more reliable estimate of ventricular function will, therefore, be obtained one to two weeks after the event.

Angina Pectoris

Prognosis of patients with chronic stable angina and multivessel coronary artery disease is also strongly influenced by left ventricular function. The Coronary Artery Surgery Study (CASS) demonstrated improved survival with coronary artery bypass

Figure 7. Left ventricular (LV) functional assessment in the evaluation of congestive heart failure (CHF).

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