Estimates And Projections For Neurological Disorders

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This document presents the GBD estimates for neurological disorders from the projected estimates for 2005, 2015 and 2030. The complete set of tables is contained in Annex 4.

Cause categories

The cause categories used in the GBD study have four levels of disaggregation and include 135 specific diseases and injuries. At the first level, overall mortality is divided into three broad groups of causes: Group I consists of communicable diseases, maternal causes, conditions arising in the perinatal period and nutritional deficiencies; Group II encompasses the noncommunicable diseases (including neuropsychiatric conditions); and Group III comprises intentional and unintentional injuries. Deaths and health states are categorically attributed to one underlying cause using the rules and conventions of the International Classification of Diseases. In some cases these rules are ambiguous, in which event the GBD 2000 followed the conventions used in the GBD 1990. It also lists the sequelae analysed for each cause category and provides relevant case definitions.


For the purpose of calculation of estimates of the global burden of disease, the neurological disorders are included from two categories: neurological disorders within the neuropsychiatric category, and neurological disorders from other categories. Neurological disorders within the neuropsychiatric category refer to the cause category listed in Group II under neuropsychiatric disorders and include epilepsy, Alzheimer and other dementias, Parkinson's disease, multiple sclerosis and migraine. Neurological disorders from other categories include diseases and injuries which have neurological sequelae and are listed elsewhere in cause category Groups I, II and III (10). The complete list used for calculation of GBD estimates for neurological disorders is given in Annex 3. Among the various neurological disorders discussed in this report, please note that for headache disorders, GBD includes migraine only (see Chapter 3.3). Also, GBD does not describe separately the burden associated with pain (see Chapter 3.7). There are also some diseases and injuries, which have neurological sequelae that have not been separately identified by the GBD study, and are not presented in this report; these include tuberculosis, HIV/AIDS, measles, low birth weight, birth asphyxia and birth trauma. The burden estimates for these conditions include the impact of neurological and other sequelae which are not separately estimated.

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