Estimates And Projections For Neurological Disorders

This document presents the GBD estimates for neurological disorders from the projected estimates for 2005, 2015 and 2030. The complete set of tables is contained in Annex 4. The cause categories used in the GBD study have four levels of disaggregation and include 135 specific diseases and injuries. At the first level, overall mortality is divided into three broad groups of causes Group I consists of communicable diseases, maternal causes, conditions arising in the perinatal period and...

Treatment Management And Cost

The discovery of the dopaminergic deficit was the major turning point in the development of rational pharmacotherapeutic approaches to PD leading to the introduction of levodopa and later dopamine agonists. With the exception of anticholinergics and amantadine, all other drugs subsequently developed (dopa-decarboxylase inhibitors, monoamine oxidase inhibitors, catechol-O-methyl transferase inhibitors) act indirectly through dopaminergic mechanisms (1,19). Functional surgery, developed many...

Headache Disorders

C o Griffin Stone, Moscrop and Co. 41 Welbeck Street London W1G 8EA England e-mail info i-h-s.org web site http www.i-h-s.org A worldwide professional society, the mission of IHS is to work with others to reduce the world burden of headache. The web site includes all published guidelines and recommendations of the IHS, and professional educational pages are planned. c o Griffin Stone, Moscrop and Co 41 Welbeck Street London W1G 8EA England e-mail info w-h-a.org web site http www.w-h-a.org A...

Box 311 Stages and symptoms of dementia Alzheimers disease

Early stage Middle stage Late stage The early stage is often overlooked. Relatives and friends (and sometimes professionals as well) see it as old age, just a normal part of the ageing process. Because the onset of the disease is gradual, it is difficult to be sure exactly when it begins. The person may have problems talking properly (language problems) loss particularly for things that have just happened not know the time of day or the day of the week become lost in familiar places have...

Disability And Burden

Anyone involved primarily in the management of chronic pain is aware that it may persist long after the initial tissue damage has healed. Pain reflects pathophysiological changes in the nervous system and they, together with changes that usually occur in patients' emotions and behaviour, have led to the conclusion that, in such cases, chronic pain is a specific health-care problem and a disease in its own right. This diagnostic category is not fully accepted among clinicians because many...

Gbd Studies And Their Key Results

In 1993, the World Bank, WHO and the Harvard School of Public Health carried out a study to assess the global burden of disease for the year 1990. The methods and findings of the 1990 GBD study have been widely published (1-3). To prepare internally consistent estimates of incidence, prevalence, duration and mortality for almost 500 sequelae of the diseases and injuries under consideration, a mathematical model, DisMod, was developed (4). The main purpose was to convert partial, often...

References

American Association for the Study of Headache and International Headache Society. Consensus statement on improving migraine management. Headache, 1998, 38 736. 2. Headache Classification Subcommittee of the International Headache Society. The international classification of headache disorders, 2nd ed. Cephalalgia, 2004, 24(Suppl. 1) 1-160. 3. Stovner LJ et al. The global burden of headache a documentation of headache prevalence and disability worldwide. Cephalalgia (accepted for publication)....

Info

Prevalence per 1000 population of individual neurological disorders Please note that prevalence and YLDs are available for the neurological cause - sequela combinations. These data are therefore provided for all neurological disorders within the neuropsychiatric category, cerebrovascular disease, combined for neuroinfections and neurological sequelae of infections (poliomyelitis, tetanus, meningitis, Japanese encephalitis, syphilis, pertussis, diphtheria, malaria), neurological sequelae...

Medicationoveruse headache

Chronic excessive use of medication to treat headache is the cause of medication-overuse headache (15), another of the chronic daily headache syndromes. Medication-overuse headache is oppressive, persistent and often at its worst on awakening in the morning. A typical history begins with episodic headache migraine or tension-type headache. The condition is treated with an analgesic or other medication for each attack. Over time, headache episodes become more frequent, as does medication intake....

Box 312 The 1066 Dementia Research Group key findings

From the development perspective, one of the key findings from the study was that caregiving in the developing world is associated with substantial economic disadvantage. A high proportion of caregivers had to cut back on their paid work in order to care. Many caregivers needed and obtained additional support, and while this was often informal unpaid care from friends and other family members, paid caregiv-ers were also relatively common. People with dementia were heavy users of health...