Stage4S Disease

A unique use of radiation therapy is for infants with stage-4S disease who have respiratory distress or compression of abdominal viscera from massive liver involvement (Paulino et al. 2002). A very low dose of radiation, three fractions of 1.5 Gy each, is extremely effective in reversing these life-threatening problems without a significant risk of long-term complications. While radiation may not be necessary immediately, it is advisable to consult a radiation oncologist as soon as possible because the child's condition can deteriorate rapidly and emergency treatment may be warranted. These infants can be treated without anesthesia or simulation because a papoose provides adequate immobilization and a clinical setup is generally possible for their palpable livers. Complex shielding is not necessary or appropriate because the liver generally fills the entire abdomen and the dose is low.

0 0

Post a comment