Immunizations are considered hazardous in OMS because it activates T cells, which are already acti-vated (Pranzatelli et al. 2002). Caution is taken to avoid livevirus immunizations and groupings of multiple vaccines. Children exposed to varicella while on immunotherapy should be treated accordingly. It is noted that sedatives, such as midazolam, fentanyl, chloral hydrate, or diphenhydramine may cause paradoxical excitation, and sometimes worsen symptoms (Tate et al. 1994). Intravenous propofol is often a short-acting efficacious alternative.

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