Neuroblastic tumors are known to be heterogeneous and their clinical behaviors are driven by complex molecular/genetic properties. The International Neu-roblastoma Pathology Classification exploits a system of age-linked evaluation of morphological indicators, to distinguish among tumors with near-identical histological features but vastly different clinical behaviors. This classification offers a unique forum for finding the morphological link between clinical behavior and tumor genetics of the enigmatic cancer of childhood.

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