Physicochemical Host Defence

The pathophysiological significance of these findings may be summarised as follows: A unique host defence mechanism has been discovered the significance of which is likely to lie way beyond protection against bacterial endotoxins. We call this mechanism the physico-chemical defence of the organism. The basis of this defence mechanism is the detergent effect of bile acids [6,31,32], One may pose the question whether or not the protection based on detergent action provides defence against enterotoxaemia only or perhaps there are other situations in which endotoxin plays a role.

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