N

N-terminal processing 33 NAb See natural antibody natural antibody 130,134,316

binding to activated cells 135 cytotoxicity 151

immunity vii, 103, 114, 117, 216, 263 activation 13, 123 in insects 107 species specific resistance v system v, vii, 12, 19 activation 123-142 killer cells SeeNK resistance 12 neopterin 271 nerve growth factor 222 nest building 353 neurodegenerative diseases 169 neuroendocrine changes 231 immune system 113 regulation of natural immunity 14 response 230 neurogenic inflammation 224, 339 neuropeptides 103,114,228 neurotransmitters 228 neutrophils 137,187,265,315 ß-arrestin 190 CD1 lb/CD 18 188 CXCL1/KC 190

CXCL2/macrophage inflammatory pro-

tein-2 (MIP-2) 190 CXCL-8/IL-8 190 CXCR1 190 CXCR2 190 CXCR4 191 E-selectin 188 extravasation 189 ICAM-1 189 LFA-1 188 L-selectin 188 Mac-1 188 PEC AM-1 189 P-selectin 188 PSGL-1 188 VLA-4 189 VLA-5 189 VLA-6 189 VLA-9 189 NF-kB 53, 54, 174 NGF See nerve growth factor nitric oxide 55

(no) production 295 synthase (iNOS) 219,295

enzyme 295 synthase (NOS) 55, 56 NK-lysin 106 NKG2D 313,333 NK 268

activating receptors 153 CCL3/MIP-la 194 cells 12, 81-85, 87-89, 108, 109, 125, 313, 355

CCL2/MCP-1 and CXCLlO/interferon-gamma-inducible protein-10 (IP-10) 194

CCL7/MCP-3 194 CCL19/MIP-3|3 194 CCR1 193, 194 CCR5 193 CCR7 193, 194 CXCL10/IP-10 193 CXCL11/I-TAC 193 CXCR4 194 (lectin) receptors 125 XCLl/lymphotactin a 194 transmembrane receptors 129 NKT cells 139

nonspecific resistance v noradrenaline 273, 362 noradrenergic systems 361 NOS See nitric oxide synthase nucleotide polymorphism See SNP

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