Planorbarius corneas Vivíparas ater Vivíparas contectus Lymnaea stagnalis Mytilus galloprovincialis


Calliphora vomitoria Galleria mellonella Estigmene acraea Lymantria dispar


Caenorhabditis elegans


Eisenia foetida


Botryllus schlosserii Ciona intestinalis

TNF-a, PDGF-AB, TGF-ßl IL-la, TNF-a IL-la, TNF-a PDGF-AB, TGF-ßl

Table V Effects of mammalian cytokines on different invertebrate functions (modified from Ottaviani).

Cytokine Function

PDGF-AB, TGF-|3l Wound repair; apoptosis

PDGF-AB, TGF-Pl, IL-8 Cell motility

PDGF-AB, TGF-pi, IL-la, TNF-a, IL-8 Cell migration

IL-la, TNF-a, IL-2 Phagocytosis; NOS production

IL-2 NK-like activity

PDGF-AB, TGF-Pl, IL-la,p, IL-2, IL-6, TNF-a,P Stress response ated coelomocyte locomotion.

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