A diet high in saturated and omega-6 fatty acids may promote cancer partly by decreasing immune function. In a study of 17 men who reduced their fat intake to less than 30 percent of calories, natural killer (NK) cell activity was markedly increased compared to baseline levels. In this study, the lower the fat content, the greater the NK cell activity.58 The exact mechanism of this inhibition was uncertain, but it may have been related to increased PGE2 production, which has an immuno-suppressive effect.
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