Section Two Acute Leukemias

11 Historical Perspectives on Acute Leukemias • 135

James F. Holland

12 Human T-Cell Lymphoma/Leukemia Virus - Associated T-Cell Lymphoma and Leukemia • 141

Bernard J. Poiesz, Michael J. Poiesz, and David Choi

13 Epidemiology and Hereditary Aspects of Acute Leukemia • 164

Julie A. Ross

14 Classification of the Acute Leukemias: Cytochemical and Morphological Considerations • 176

Nukhet N. Tuzuner and John M. Bennett

15 Immunobiology of Acute Leukemia • 194

Elisabeth Paietta

16 Cytogenetics of Acute Leukemia • 232

Gordon Dewald and Mark Litzow

17 Diagnosis and Treatment of Childhood Acute Lymphoblastic Leukemia • 249

Susan M. McKenna

18 Diagnosis and Treatment of Adult Acute Lymphoblastic Leukemia • 273

Dieter Hoelzer and Nicola Gokbuget

19 Diagnosis and Treatment of Childhood Acute Myelogenous Leukemia • 306

Howard J. Weinstein

20 Diagnosis and Treatment of Adult Acute Myeloid Leukemia Other Than Acute Promyelocytic Leukemia • 316

Peter H. Wiernik

21 Acute Promyelocytic Leukemia • 336

Peter H. Wiernik, Robert E. Gallagher, and Martin S. Tallman

22 Therapy-Related Acute Myelogenous Leukemia • 370

Dorothy J. Park and H. Phillip Koeffler

23 Myelodysplastic Syndromes • 395

Kenneth B. Miller

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