Section Three Myeloma And Related Disorders

24 History of Multiple Myeloma • 415

Robert A. Kyle

25 Cytokines and Signal Transduction in Multiple Myeloma • 424

Dharminder Chauhan and Kenneth C. Anderson

26 Epidemiology of Multiple Myeloma • 434

Linda M. Brown, Dalsu Baris, and Susan S. Devesa

27 Immunoglobulins and Laboratory Recognition of Monoclonal Proteins • 446

Robert A. Kyle, Jerry A. Katzmann, John A. Lust, and Angela Dispenzieri

28 Cytogenetic Abnormalities in the Monoclonal Gammopathies • 470

Rafael Fonseca, P. Leif Bergsagel, and W. Michael Kuehl

29 Molecular Genetics in Multiple Myeloma and Related Disorders • 477

Matt Rowley and Brian Van Ness

30 Staging, Kinetics, and Prognosis in Multiple Myeloma • 488

Philip R. Greipp and Robert A. Kyle

31 Diagnosis and Treatment of Multiple Myeloma • 527

Douglas E. Joshua and John Gibson

32 Syndromes and Special Presentations Associated with Plasma Cell Myeloma • 547

Daniel E. Bergsagel and Waldemar Pruzanski

33 Waldenstrom's Macroglobulinemia • 562

Meletios A. Dimopoulos

34 Heavy-Chain Disease • 573

Dietlind Wahner-Roedler and Robert A. Kyle

Morie A. Gertz and Robert A. Kyle

36 Monoclonal Gammopathies of Undetermined Significance • 619

Robert A. Kyle and S. Vincent Rajkumar SECTION FOUR. LYMPHOMA

37 Historical Overview of Malignant Lymphoma • 651

Alan C. Aisenberg

38 Genetic Factors in Lymphomagenesis • 662

Januario E. Castro and Thomas J. Kipps

39 Epidemiology and Hereditary Aspects of Malignant Lymphoma and Hodgkin's Disease • 673

Seymour Grufferman

40 Pathology of Non-Hodgkin's Lymphomas and Hodgkin's Disease • 687

L. Jeffrey Medeiros and Elaine S. Jaffe

41 Immunology of the Lymphomas • 734

Rupesh Parikh and Howard Ozer

42 Cytogenetics of Non-Hodgkin's Lymphoma and Hodgkin's Disease • 766

Krzysztof Mrozek and Clara D. Bloomfield

43 Diagnosis and Treatment of Hodgkin's Disease • 796

Monica Balzarotti, Peter H. Wiernik, and Armando Santoro

44 Radiotherapeutic Management of Lymphomas • 818

Sandra E. Mitchell and Nancy Price Mendenhall

45 Diagnosis and Treatment of Non-Hodgkin's Lymphoma of Adults • 827

Julie M. Vose, Philip J. Bierman, and James O. Armitage

46 Non-Hodgkin's Lymphoma of Childhood • 843

Sheila Weitzman and Robert J. Arceci

47 Lymphoma in Other Diseases • 862

Barbara K. Dunn and Dan L. Longo

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