Red Cell Mass Demonstration of an Absolute Erythrocytosis

A diagnosis of an absolute erythrocytosis can only be made when an individual's RCM measurement is more than 25 percent above their mean predicted value. The RCM result and predicted values should be expressed in terms of the patient's surface area rather than body weight. As fat is relatively avascular, results expressed in terms of total body weight lack precision in the obese patient. Using surface area to calculate the predicted RCM, 98 percent of males and 99 percent of females fell within ± 25 percent of the mean value.91 Should a patient's RCM fall within the reference range the term apparent erythrocytosis should be applied.

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