Pathogenesis Of Pv

PV is thought to result from the clonal expansion of a single transformed multipotent stem cell. Progenitors from patients with PV demonstrate abnormal growth responses to several growth factors, suggesting the presence of a defect in a signaling pathway common to different growth factors. PV is also associated with nonrandom cytogenetic abnormalities, the chromosomal location of these changes suggesting the position of genes important to the pathogenesis of the disease. The identification of causal genes may provide much needed diagnostic markers for the disease, allow specific therapy of the molecular and cellular defects, and provide insights into fundamental issues of stem cell behavior.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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