Clonality Markers

The marrow karyotype is nearly always normal in ET. The 1 to 2 percent of ET patients who have variable karyotypic abnormalities might represent a subgroup with a poorer prognosis.8 The use of X chromosome-linked probes to establish clonality has limitations in female patients over 60 years, 25 to 30 percent of whom have apparent clonal granulocytes.9,10 In younger patients, only half can be shown to have clonal hemopoiesis, as discussed earlier, but this finding carries diagnostic significance.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook


Post a comment