Clinical Manifestations

With the use of routine screening, the number of patients with CLL who are asymptomatic at diagnosis has increased to about 40 percent.1,2 The diagnosis is often incidental and detected during a routine examination or during preoperative evaluation. About 60 percent of patients with CLL present with various symptomatology, including constitutional symptoms. When constitutional symptomatologies are present, the most

Table 7-1. Phenotype of B-cell Lymphoid Leukemias Type of Leukemia CD5 CD10 CD19

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