B

Figure 8—1. Peripheral blood smears from patients with hairy cell leukemia (A) and splenic lymphoma with circulating villous lymphocytes (B). The hairy cells are small to medium in size, have ovoid or reniform nuclei with finely clumped chromatin, and demonstrate abundant, frayed gray-blue cytoplasm. In comparison, the circulating villous lymphocytes have increased nuclear to cytoplasmic ratios, round nuclei with coarse chromatin, and basophilic cytoplasm with short, often polar, projections (Wright's stain, x 1,500).

Figure 8—1. Peripheral blood smears from patients with hairy cell leukemia (A) and splenic lymphoma with circulating villous lymphocytes (B). The hairy cells are small to medium in size, have ovoid or reniform nuclei with finely clumped chromatin, and demonstrate abundant, frayed gray-blue cytoplasm. In comparison, the circulating villous lymphocytes have increased nuclear to cytoplasmic ratios, round nuclei with coarse chromatin, and basophilic cytoplasm with short, often polar, projections (Wright's stain, x 1,500).

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