Local Applications And Chemotherapy

One of the most interesting and potentially important minimally invasive therapies for brain tumors is the future potential for local applications of gene therapy and chemotherapy (also discussed in Chapters 13 and 14). Infusion technology with catheters in tumor or ventricles for convection-enhanced delivery is one example; another is the application of cells or slow-release polymers to the tumor bed (57-59). It may be possible for the patient then to benefit from minimally invasive techniques for direct and local chemotherapy (60,61) and gene therapy (62,63).

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