Polymerase chain reaction and other molecular techniques have revolutionized analysis of the human genome. This is most striking in the rapid development of techniques that use PCR for the detection of mutations that cause inherited genetic disease. Advances in technology have allowed physicians to confirm difficult clinical diagnoses and to offer prenatal diagnosis and carrier detection, as well as susceptibility testing. In addition, detection of mutations that cause resistance to antiviral drugs is now a cornerstone in the therapy of viral diseases such as HIV and HCV. It is expected that with further developments in automation and technological advances many of the techniques described in this chapter (which are still relatively costly and labor-intensive) will contribute to the routine use of molecular diagnostic testing in clinical practice.

Was this article helpful?

0 0
Pregnancy Guide

Pregnancy Guide

A Beginner's Guide to Healthy Pregnancy. If you suspect, or know, that you are pregnant, we ho pe you have already visited your doctor. Presuming that you have confirmed your suspicions and that this is your first child, or that you wish to take better care of yourself d uring pregnancy than you did during your other pregnancies; you have come to the right place.

Get My Free Ebook

Post a comment