The promise of pharmacogenetics is that "trial-and-error" practices in selecting pharmacotherapies will be replaced by informed tailoring of treatments to the genetic makeup of individual patients. In its full realization, pharmacogenetics would revolutionize the practice of medicine. The premise of pharma-cogenetics is clearly not revolutionary, but only in rare cases have pharmacogenetic practices been routinely adopted. Although it is not reasonable to presume that pharmacogenet-ics will be capable of individualizing medicine in the near future, it is realistic to expect that molecular genetics will continue, in an incremental fashion, to improve our ability to diagnose and treat illnesses with the right drug at the right dose. Step by step we get closer to the goal of personalized medicine.

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