Weaning

• Bronchospasm may increase on lightening sedation due to awareness of endotracheal tube and increased coughing.

• May need trial of extubation while still on high FIO2

• Consider extubation under inhalational or short-acting IV sedation.

space out intervals between p2 agonist nebulisers. Convert other antiasthmatic drugs to oral medication. Theophylline doses should be adjusted to ensure therapeutic levels.

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