Techniques

Numerous including haemofiltration, haemodiafiltration, ultrafiltration, continuous ultrafiltration with intermittent dialysis (CUPID). Filtrate is usually removed at 1-2l/h and fluid balance adjusted by varying the fluid replacement rate. High volume haemofiltration involves much higher clearances (e.g. 351 in a 4h period) though variable outcomes are reported in randomised studies.

Creatinine and potassium clearances are higher with diafiltration though filtration alone is usually sufficient provided an adequate ultrafiltrate volume is achieved (1000ml/h = creatinine clearance of 16ml/min).

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