Sideeffectscomplications

• Sodium and water retention (especially with mineralocorticoids)

• Hypoadrenal crisis if stopped abruptly after prolonged treatment

• Immunosuppressive — possibly increased infection risk (q.v.)

• Neutrophilia

• Impaired glucose tolerance/diabetes mellitus

• Hypokalaemic alkalosis

• Osteoporosis, proximal myopathy (long-term use)

• Increased susceptibility to peptic ulcer disease and GI bleeding

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