Alprostadil has similar effects to epoprostanil but is less potent. As it is metabolised in the lungs, systemic vasodilatation effects are usually minimal. This may be an important advantage in the shocked patient. Major uses in intensive care are for anticoagulation of filter circuits, digital vasculitis/ischaemia and pulmonary hypertension.

For extracorporeal use citrate has advantages over heparin in that it has no known antiplatelet activity, is readily filtered by a haemofilter (reducing systemic anticoagulation), and is overwhelmed and neutralised when returned to central venous blood.

Warfarin is given orally and needs 48-72h to develop its effect. It can be reversed by fresh frozen plasma or low doses (1mg) of vitamin K.

Activated Protein C has anti-inflammatory and pro-fibrinolytic properties in addition to its anticoagulant actions.


Cure Tennis Elbow Without Surgery

Cure Tennis Elbow Without Surgery

Everything you wanted to know about. How To Cure Tennis Elbow. Are you an athlete who suffers from tennis elbow? Contrary to popular opinion, most people who suffer from tennis elbow do not even play tennis. They get this condition, which is a torn tendon in the elbow, from the strain of using the same motions with the arm, repeatedly. If you have tennis elbow, you understand how the pain can disrupt your day.

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