Guillain Barre syndrome

This is an immunologically-mediated, acute demyelinating polyradiculopathy. Viral infections and immunisations are common antecedents. The syndrome includes a progressive, areflexic motor weakness (often symmetrical, ascending and involving cranial nerves including facial, bulbar and extraocular) with progression over days to weeks. There are often minor sensory disturbances (e.g. paraesthesiae). Autonomic dysfunction is not unusual. There is no increase in cell count on CSF examination but protein levels usually rise progressively (>0.4 g/l). Nerve conduction studies show slow conduction velocities with prolonged F waves. Other features include muscle tenderness and back pain. The major contributors to morbidity and mortality are respiratory muscle weakness and autonomic dysfunction (hypotension, hypertension, arrhythmias, ileus and urinary retention).

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

Get My Free Ebook

Post a comment