Colloid osmotic pressure

Colloid osmotic pressure (COP) is the pressure required to prevent net fluid movement between two solutions separated by a selectively permeable membrane when one contains a greater colloid concentration than the other. The selectively permeable membrane should impede the passage of colloid molecules but not small ions and water. COP is determined by number of molecules rather than type. However, most solutions exhibit non-ideal behaviour due to intermolecular interactions and electrostatic effects. Hence COP cannot be inferred from plasma protein concentrations; it must be measured.

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