Clinical features

• Non-specific signs including pyrexia (especially swinging), neutrophilia, falling platelet count, increasing metabolic acidosis, circulatory instability

• Abdominal distension ± localised discomfort, peritonism

• Abdominal mass, e.g. gall bladder, pseudocyst, abscess

• Failure to tolerate enteral feed/large nasogastric aspirates

• Pleural effusion (if subdiaphragmatic sepsis)

• Diarrhoea (if pelvic sepsis)

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