Causes of severe weakness Common in ICU

Metabolic myopathies

Prolonged effects of muscle relaxants

Critical illness neuropathy or myopathy

Guillain-Barré syndrome

Myasthenia gravis

Pontine CVA

Substance abuse (especially benzene ring compounds)

Uncommon in ICU

Chronic relapsing polyneuritis Endocrine myopathies Sarcoid neuropathy Poliomyelitis Diphtheria

Carcinomatous neuropathy

Porphyria

Botulism

Familial periodic paralysis Multiple sclerosis Lead poisoning Organophosphorus poisoning

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