Susceptibility

The susceptibility artefact is exaggerated by gradient echoplanar imaging, typically causing signal loss in inferior temporal and orbitofrontal brain regions close to bone or sinuses. The problem is further compounded if subjects are asked to speak during scanning, since slight deformations of the sinuses associated with overt articulation can cause changes in susceptibility artefact which can mimic signal changes due to speech-related neural activity. If overt articulation is necessary to monitor the subject's performance on the experimental task, then it is advisable to design the sequence so that images are not acquired while the subject is speaking.

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