Residual effects

Residual effects can be a problem especially when long-acting drugs are used repeatedly. (60,) Dosage is important here, since residual effects increase in both magnitude and duration as the dose is increased. It should be remembered that hypnotics are the only class of drugs in which the main therapeutic effect (drowsiness) is identical with the main unwanted effect; the two are merely separated by 8 h in time! A short-acting hypnotic compound will be devoid of residual effects the next day, but the patient may wake early. After taking a longer-acting compound, sleep may be prolonged but hangover effects pronounced.

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