Possible preventive measures

Several studies suggest that long-term treatment with zidovudine may produce a prophylactic effect in symptomatic patients with HIV infection, reducing the risk for development of HIV-associated dementia. This effect, however, seems to be time limited: in a recent retrospective study carried out on a longitudinal cohort of 1109 patients with AIDS/15' the use of zidovudine for a period of 6 to 18 months was associated with a reduced risk of dementia, whereas treatment for longer than 18 months was not beneficial.

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