The target serum phenytoin concentration range is between 40 and 80 pmol/1 (but see Fig 2). Higher concentrations are associated with an increased risk of toxicity.

The blood sample can be taken at any time after the last dose. Because phenytoin kinetics are non-linear (i.e. the amount in the body increases disproportionately with increases in dosage) dosages should not be changed more than every few weeks and should be limited to changes of no more than 25 or 50 mg in the total daily dose.

5 Secrets to Lasting Longer In The Bedroom

5 Secrets to Lasting Longer In The Bedroom

How to increase your staying power to extend your pleasure-and hers. There are many techniques, exercises and even devices, aids, and drugs to help you last longer in the bedroom. However, in most cases, the main reason most guys don't last long is due to what's going on in their minds, not their bodies.

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