Pharmacology of stimulant medication

Methylphenidate is rapidly absorbed and easily crosses the blood- brain barrier. The effects of this stimulant are seen in 30 min. Its peak plasma level occurs in 1 to 2 h, and its half peak level in 3 h. Its absorption is unaffected by meals. (123) Of primary clinical importance is the duration of its effect; the effects of methylphenidate last only 1 to 4 h. Therefore, the medication must be taken repeatedly. The effect of sustained-release dexedrine (Dexedrine Spansules) lasts 9 h. (124) Sustained-release methylphenidate (Ritalin Sustained Release) is designed to have the same impact as 10 mg of regular methylphenidate taken twice daily. However, sustained-release methylphenidate may have a variable and slow onset of effect; it may take 3 h to take effect, and the effect may last only 5 h.(!24)

Breaking Bulimia

Breaking Bulimia

We have all been there: turning to the refrigerator if feeling lonely or bored or indulging in seconds or thirds if strained. But if you suffer from bulimia, the from time to time urge to overeat is more like an obsession.

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