Peptic ulcer disease

Peptic ulcer disease occurs when the balance between stomach acid and mucosal defence factors is disrupted. Gastric acid, Helicobacter pylori, and non-steroidal anti-inflammatory drugs are the most important risk factors in the development of peptic ulcers. (49> The majority of patients with peptic ulcer disease present with epigastric pain that begins 1 to 3 h after eating. Treatment is aimed at reducing gastric acid (e.g. using cimetidine and ranitidine), improving mucosal defences (with, for instance, sucralfate), and/or eradicating H. pylori (antibiotics).

On examination, at least half of the patients initially suspected of having peptic ulcer disease do not have evidence of an ulcer. (59 Among patients with non-ulcer dyspepsia, psychiatric comorbidity is high. Magni reported that 87 per cent of patients with non-ulcer dyspepsia have one or more anxiety disorders compared with 25 per cent of those with dyspepsia where there is endoscopic evidence of ulcer. (51 To date, studies have not demonstrated that behavioural or psychopharmacological interventions in patients with non-ulcer dyspepsia are efficacious. (52)

Herbal Remedies For Acid Reflux

Herbal Remedies For Acid Reflux

Gastroesophageal reflux disease is the medical term for what we know as acid reflux. Acid reflux occurs when the stomach releases its liquid back into the esophagus, causing inflammation and damage to the esophageal lining. The regurgitated acid most often consists of a few compoundsbr acid, bile, and pepsin.

Get My Free Ebook


Post a comment