Neuromuscular disorders

Sleep disturbances have been described in many patients with neuromuscular disorders including myotonic dystrophy, motor neurone disease, neuromuscular junctional disorders, and polyneuropathies. Sleep disturbance has generally been secondary to involvement of the respiratory muscles, the phrenic and intercostal nerves, or the neuromuscular junctions of the respiratory and oropharyngeal muscles. The most common complaint is excessive daytime sleepiness resulting from repeated arousals and sleep fragmentation associated with apnoeas, hypopneas, and hypoventilation. Similar sleep disturbance is also seen in the acute convalescent stages of poliomyelitis.

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