A number of studies(2 ,27,28 and 29> have shown that elderly depressed patients have a two- to threefold increase in expected mortality over periods of between 1 and 4

years, with an excess of deaths due to cardiovascular causes. This is not simply due to depressed people experiencing greater overall physical ill-health. (29)

O'Brien and Ames(39 have proposed several possible mechanisms for the increased mortality in depression: comorbid physical illness; occult illness (e.g. a carcinoma); illness effects (e.g. related to pneumonia secondary to psychomotor retardation); treatment effects; biological effects, such as abnormality of the hypothalamic-pituitary- adrenal axis or endocrine abnormalities which may affect the immune system. Undertreatment is another plausible explanation. (31 In most studies, suicide comprised a very small percentage of deaths(2 ,2Z) and so is not the main cause of additional mortality.

Anxiety and Depression 101

Anxiety and Depression 101

Everything you ever wanted to know about. We have been discussing depression and anxiety and how different information that is out on the market only seems to target one particular cure for these two common conditions that seem to walk hand in hand.

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