Measuring brain receptors and neurochemistry5

Many neurochemical hypotheses, generated by post-mortem and animal data, can be rigorously tested with PET and SPET in the living brain whilst avoiding many of the confounding variables inherent in other techniques. Many receptor systems can be studied ( T§b.!e..1). However, the rate of discovery of new radiotracers, suitable for use in humans, is relatively slow. Many conditions have to be satisfied to produce a suitable radiotracer for human use including blood-brain barrier permeability, high specific binding, receptor selectivity, absence of radioactive metabolites, and adequate modelling of tracer kinetics ( Plate.6).

Breaking Bulimia

Breaking Bulimia

We have all been there: turning to the refrigerator if feeling lonely or bored or indulging in seconds or thirds if strained. But if you suffer from bulimia, the from time to time urge to overeat is more like an obsession.

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