Macroscopic findings

Four studies examined macroscopic measures such as the gross brain morphology,(43) brain weight and ventricular volume,(44) and the area or volume of specific regions such as the hippocampus, parahippocampal gyrus,(45) striatum, globus pallidus, and corpus callosum.(4446) In comparison to schizophrenic patients and/or non-psychiatric control subjects, patients with affective disorders revealed caudate lesions, (49 reduced area of the right parahippocampal gyrus,(49 increased brain and reduced ventricular volume.(44)

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