Introduction

The course of schizophrenia is as variable as its symptoms. Systematic investigations of the courses of the psychoses were initiated by Kraepelin who believed that, in the absence of demonstrable brain pathology and aetiology, a common outcome into 'psychic weakness' of the clinical syndromes he grouped together as dementia praecox would provide a validity test for the disease entity. Later, Kraepelin revised his claim that the prognosis of dementia praecox was invariably poor and noted that 'permanent cures' had occurred in about 15 per cent of his cases.(1) Subsequent longitudinal studies have confirmed the striking variability of course as one of the salient characteristic of the 'natural history' of schizophrenia.

Funny Wiring Autism

Funny Wiring Autism

Autism is a developmental disorder that manifests itself in early childhood and affects the functioning of the brain, primarily in the areas of social interaction and communication. Children with autism look like other children but do not play or behave like other children. They must struggle daily to cope and connect with the world around them.

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