Heroin metabolism

Diamorphine (half-life 2 min) is rapidly metabolized to the psychoactive intermediate 6-mono-acetyl-morphine (the only metabolite that indicates the consumption of heroin specifically as opposed to other opiates) by blood esterases before being converted to morphine (half-life 3 h). Morphine is subsequently metabolized by the cytochrome P-450 system (Cyp2D6) in the liver to codeine which undergoes conjugation before excretion in the urine. In most subjects, about 10 per cent of ingested codeine is converted into morphine, thereby giving a clinically false-positive test result for heroin/morphine. (3)

Do Not Panic

Do Not Panic

This guide Don't Panic has tips and additional information on what you should do when you are experiencing an anxiety or panic attack. With so much going on in the world today with taking care of your family, working full time, dealing with office politics and other things, you could experience a serious meltdown. All of these things could at one point cause you to stress out and snap.

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