Diaschisis (from the Greek diascizw, I separate at a distance) refers to sudden and reversible clinical (usually negative) phenomena seen in the wake of 'shock' caused by localized lesions of the central nervous system. Its defining element is that it cannot be explained in terms of the mere extension and localization of the brain lesion. For example, a hemiplegia includes more functional deficits than the lesion can explain. Inhibition differs from diaschisis in that the former results from the activity of known nervous connection.

Two conclusions follow:

1. some mental symptoms may result from diaschisis, i.e. have no direct anatomical localization;

2. because chronogenetically localized functions are more unstable, their disorder is likely to give rise to more mental symptoms.

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