Comments

While in terms of professional guidelines it would be considered good practice to go through these steps in patients responding poorly or frankly resistant, most are largely empirically derived, and such evidence as there is does not encourage optimism about their overall likelihood of success.

As was noted, the one treatment of established efficacy in resistant schizophrenia is clozapine. (65> While in individual cases impressive benefits may become evident, especially in quality-of-life parameters, improvements attributable to clozapine over standard drugs are far from dramatic. Despite this, clozapine is probably underutilized and should be more readily considered in treatment of resistant cases. (See Chapter6.2..i5 for further discussion of new-generation antipsychotics.)

Funny Wiring Autism

Funny Wiring Autism

Autism is a developmental disorder that manifests itself in early childhood and affects the functioning of the brain, primarily in the areas of social interaction and communication. Children with autism look like other children but do not play or behave like other children. They must struggle daily to cope and connect with the world around them.

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