Clinical features and course of illness

Huntington' disease is an inherited neuropsychiatric disorder mainly affecting the striatum and its direct connections. It is characterized by a triad of clinical features that are common to most diseases of the striatum and its direct connections: a non-aphasic dementia, depression and other disorders of mood, and a variety of dyskinesias, most typically chorea.(23) Chorea, from the Greek word for 'dance', describes involuntary non-stereotyped jerky movements. The illness, insidious in onset, may begin with any of these three features. Patients who present initially to psychiatrists usually have depression, often with suicidal thoughts or attempts, dementia, or loss of temper. The onset may occur at any time from early childhood to old age, most frequently between 35 and 45 years of age. Once the illness begins, sufferers gradually deteriorate over many years in their cognitive and motor functioning and end in a persistent vegetative state with almost complete loss of voluntary motor function. Death occurs after about 16 years (although some patients live much longer) and is usually caused by inanition or aspiration pneumonia. Some patients die earlier from suicide or subdural haematoma caused by a fall.

Break Free From Passive Aggression

Break Free From Passive Aggression

This guide is meant to be of use for anyone who is keen on developing a better understanding of PAB, to help/support concerned people to discover various methods for helping others, also, to serve passive aggressive people as a tool for self-help.

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