Bipolar affective disorder

The use of neurosurgery for bipolar affective disorder was delayed until the early 1980s because of concerns that manic phases of the disorder would become disinhibited. In fact, reports indicate that, if anything, there is a greater modulation of manic than depressive phases. (16> The only type of lesion used in this disorder has been stereotactic subcaudate tractotomy, and this indication accounted for 25 per cent of the operations carried out at the Geoffrey Knight Unit in London during the 1980s.(17)

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